I was recently prescribed Cymbalta for depression/anxiety/pain. I'm starting out on 30mg for a week then going up to 60mg. I've had two doses so far and I'm definitely starting to feel good effects. Learn about Cymbalta (Duloxetine Hcl) may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related medications. Nausea, headache and a dry mouth are among the most common side effects of Cymbalta. In rare cases, patients have suffered serious — and sometimes fatal — side effects, including liver damage, abnormal bleeding, and suicidal thoughts and behaviors. Have been on Cymbalta 60mg 2xd about 7 yrs. started tapering off early Dec. 2016. Dr. Advised 60mg 1xd for 8 wks. Then 30mg for 8 wks, back to 30mg 2xd for a week if withdrawal symptoms. Consumer information about the medication DULOXETINE - ORAL (Cymbalta), includes side effects, drug interactions, recommended dosages, and storage information. Read more about the prescription drug DULOXETINE - ORAL. Duloxetine is used to treat depression and generalized anxiety disorder (GAD; excessive worry and tension that disrupts daily life and lasts for 6 months or longer). Cymbalta is the brand name for duloxetine, an antidepressant prescribed to treat the symptoms of depression. In addition to depression, doctors can prescribe Cymbalta to treat anxiety that lasts. Cymbalta is an antidepressant approved to treat mood and pain disorders. It was one of Eli Lilly’s most profitable drugs. It works by preventing the body from reabsorbing two neurotransmitters: serotonin and norepinephrine. Cymbalta (duloxetine), a drug prescribed for neuropathic pain associated with diabetic peripheral neuropathy, depression, and anxiety. Side effect, dosage, and drug interaction information included. Cymbalta, or Duloxetine is a serotonin-norepinephrine reuptake inhibitor used to treat depression and neurological pain. Find out about the uses and risks.